Registration of hemodynamic indices in physiological experiment
Abstract
Methods and devices for registration of blood pressure parameters of heart contractions and a number of other hemodynamic indices in laboratory animals are described. Basic characteristics of mercury manometer as a standard laboratory device and the possibility of graphical record of its readings are also considered. Moreover, the scheme and structural peculiarities of membrane pressure devices, as well as apparatuses for registration of pulse fluctuation the change of heart contraction frequency and other characteristics are shown. For the experimenters to get the above mentioned results tenzotransistors, termistors and other state-of-the-art microelectronics sensing elements were used. The possibility of applying modern biomedical technologies to physiological studies of laboratory animals is described. Some variants of such devices and sensing elements for registration of blood pressure and other liquid mediums of the organism as well as frequency and other parameters of blood contraction are discussed. The article contains examples of actual record of changes in hemodynamic characteristics in case of experimental nitrite hypoxia in rats.
Keywords:
hemodynamic, blood pressure, registration of physiological function, laboratory animals
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Articles of Biological Communications are open access distributed under the terms of the License Agreement with Saint Petersburg State University, which permits to the authors unrestricted distribution and self-archiving free of charge.