Symbiogenetics: molecular models, evolutionary strategies and applied aspects
The great majority of organisms undergo their living cycles as the components of supra-organismal communities in which a broad spectrum of competitive, antagonistic and cooperative interactions are implemented. Among them, mutualistic cooperation is of special interest since it usually involves the partners’ genetic integration resulted in formation of the super-species genetic systems — metagenomes, hologenomes, symbiogenomes. A degree of this integration ranges from the cross-regulations of partners’ genes via the highly specific signaling interactions to the partners’ genetic recombination resulted in emergence of mosaic genomes of eukaryotic organisms.
The cooperative strategies of the organism development, adaptation and evolution represents a subject of symbiogenetics which is a novel and actively developing biological area aimed to study the genetic integration of distant species in different types of biological communities. In this issue of Biological Communications, we will highlight the most studied models of symbiogenetics represented by bacteria-plant and bacteria-animal cooperations. They allow us to address a broad spectrum of genetic phenomena including symbiogenesis as an evolutionary pathway connecting the autonomously living bacteria and cellular organelles. The genetically specialized host-pathogen systems will also be discussed as the notable examples of the stable supra-organismal systems which, in many cases, may be reorganized into beneficial symbioses. The models and algorithms of symbiotic engineering for constructing the novel genomes and supra-organismal systems to be used for the agronomic, biomedical and environment-protective purposes will also be presented.
The manuscripts submitted for consideration in this special issue should not have been published elsewhere (with exception of presenting results at scientific conferences). All manuscripts will be peer-reviewed.
The coverage of this Issue includes but is not limited to following topics:
- Plant-microbial cooperation;
- Host-pathogen interactions;
- Metagenomics, metatransriptomics and metaproteomics in symbiogenetics;
- Symbiogenesis and organellogenesis;
- Evolution of supra-organismal systems;
- Horizontal and endosymbiotic gene transfer;
- Molecular modelling to study signal transduction;
- Population genomics of symbiotic microorganisms;
- Extremophilic microbial communities;
- Human microbiome;
- Synthetic microbial consortia for agriculture, biomedicine and environment protection.
Deadline for article submission to this special issue is September 1, 2020.